Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p160 | Cell biology: osteoblasts and bone formation | ECTS2016

Effect of melatonin on in vitro bone remodelling and blood supply

Gohin Stephanie , Pereira Marie , Belgrave Naomi Weekes , Lee Ji Sun , Tompkins Hayley , Orriss Isabel , Chenu Chantal

Melatonin is a neuro-hormone released primarily from the pineal gland, which has been shown to have bone anabolic effect, although it is still unclear whether its skeletal action is directly mediated by receptors expressed on bone cells or is indirect. In this study, we examined melatonin’s effects on bone cellular activities in vitro and tested whether it modifies angiogenesis and blood flow to bone, which are both essential for bone formation.<p class="abst...